KITLG and atherosclerosis: Previous researches have shown an increased risk of major adverse cardiovascular events (MACE) in patients with SCF, such as atherosclerosis [2], acute coronary syndrome [3], nonobstructive myocardial infarction [4], malignant arrhythmia [5], and metabolic syndrome, which was explained by vascular endothelial dysfunction, microangiopathy, inflammation, atherosclerosis, platelet activity and dysfunction, and insulin resistance [2, 6–10].