Of the 30 loci of susceptibility to CAD previously reported in individuals of European and South Asian descent, PEMT, APOE, LDLR, COL4A1, LIPA, APOA1 APOA5, PPAP2B, and PCSK9 also present phenotypic characteristics directly relevant to the disease [8]. The gene discussed is APOA1; the disease is coronary artery disorder.