This may be due to the relatively small number of eyes included in the study (18 eyes), the variability in the anti-VEGF agent used (bevacizumab in 14 eyes, aflibercept in 3 eyes, and ranibizumab in 1 eye), the inclusion of 2 different causes of macular edema (DME in 13 eyes and CRVO in 5 eyes), the short duration of treatment (1 month), and the use of vascular density measurements from the machine software. The gene discussed is VEGFA; the disease is macular retinal edema.