Figures 1D,E show that CLP sepsis markedly decreased the values of EF% (34.3%) and % FS (42.8%) in WT septic mice and 48.2 and 56.5% in HSPA12B–/– septic mice, when compared with the respective sham controls. HSPA12B–/– septic mice exhibited a lower EF% (20.5%) and FS% (22.8%) than in WT septic mice. There was no significant difference in the baseline values of EF% and %FS between WT and HSPA12B–/– mice. Here, HSPA12B is linked to Sepsis.