– All patients in the MET group had sputum smear reversion after 2 months of intensive phase TB therapy – Increases in MAP1LC3B, SOD, and interferon before and after the observation period were significant following MET treatment (p < 0.005) – During the intensive period of anti-TB therapy MAP1LC3B and interferon displayed significant changes (p < 0.005), and SOD showed no significant changes – MAP1LC3B is representative of autophagy whilst SOD induces autophagy – Interferon is responsible for protecting against TB infection. The gene discussed is MAP1LC3B; the disease is tuberculosis.