In conclusion, these data indicate that both miR-339-5p and miR-424-5p can directly influence VEGF expression and potentially contribute to abnormal VEGF level and function in PCOS; miRNAs were found to differ between women without PCOS in the follicular phase of the menstrual cycle and anovulatory PCOS women, but when age and BMI were matched, there were no associations with AMH and the metabolic parameters. The gene discussed is AMH; the disease is polycystic ovary syndrome.