Conversely, the genes closest to the four SCR exclusively present in control mice include COL19A1 which is involved in developmental processes by encoding a collagen protein differently expressed in amyotrophic lateral sclerosis; NECTIN3 which is likewise involved in development and encodes an immunoglobulin-like cell adhesion molecule linking receptor 1 of corticotropin-releasing hormone to stress-induced memory deficits; SUDS3 which modulates cell processes and is member of chromatin remodeling complexes; and GM8179 which is a lncRNA gene. The gene discussed is SUDS3; the disease is amyotrophic lateral sclerosis.