NECTIN3 and amyotrophic lateral sclerosis: On the other hand, in control SCR, the genes closest to two of them, respectively, encode the collagen of amyotrophic lateral sclerosis (Col19a1) and a cell adhesion protein (Nectin3), while the genes closest to the other SCR are, respectively, involved in chromatin remodeling (Suds3) and post-transcriptional regulation (lncRNA).