When compared to the control group, the periodontitis group presented in the gingival tissue samples a significant (p < 0.05) increase in mRNA expression of resistin and a significant (p < 0.05) decrease in mRNA expression of adiponectin as well as of leptin and its functional receptor (Figures 2(a)–2(d)). The gene discussed is ADIPOQ; the disease is periodontitis.