Through GSEA analysis of the ZIKV chip, we found that after ZIKV infection, IFN-α signaling pathway was significantly enriched (nominal p value = 0, FDR = 0.0159) (Supplementary Table 1), and 70 IFN-α pathway genes were significantly upregulated (Figures 6(a) and 6(b)). Here, IFNA1 is linked to Zika virus infectious disease.