Importantly, many of the well-validated APS1 antigens, including specific members of the cytochrome P450 family (CYP1A2, CYP21A1, CYP11A1, CYP17A1), lung disease-associated antigen KCRNG, as well as IL17A, IL17F, and IL22, among others were well represented (Figure 1B). The gene discussed is AIRE; the disease is glycogen storage disease VI.