LPIN1 and rhabdomyolysis: Mutations in LPIN1 were gradually recognized as the one of the most common causes of recurrent rhabdomyolysis, as the incidence reported for patients suffering from severe rhabdomyolysis with onset before age 6 years and creatine kinase (CK) > 10,000 U/L reaches 46% by a series of studies [1, 5].