UBC and cancer: The KEGG pathway analysis suggested that genes involved in the key modules were mostly enriched in ubiquitin mediated proteolysis, spliceosome, Endocytosis, mRNA surveillance pathway, microRNAs in cancer, Pathways in cancer, proteoglycans in cancer, cell cycle, VEGF signaling pathway, FoxO signaling pathway, PI3K-Akt signaling pathway, HIF-1 signaling pathway and Ras signaling pathway.