Subsequently, the results of KEGG pathway analysis revealed that the target genes of miR-20a were highly enriched in TGF-beta signaling pathway, pathways in cancer, p53 signaling pathway, cell cycle, Proteoglycans in cancer, sphingolipid signaling pathway, colorectal cancer, PI3K-Akt signaling pathway, viral carcinogenesis and MAPK signaling pathway. Here, TP53 is linked to colorectal cancer.