Cox regression test of survival data indicated that increased ANGPTL1 (≥5.119) [P = 5.731 × 10−3], ANGPTL2 (≥10.456) [P = 1.467 × 10−2], ANGPTL4 (≥7.062) [P = 1.799 × 10−2], ANGPTL5 (≥0.540) [P = 1.139 × 10−2], and ANGPTL7 (≥2.174) [P = 3.051 × 10−2] mRNA levels are associated with poor overall survival (OS) of GC. This evidence concerns the gene ANGPTL5 and gastric cancer.