Our results find support in epidemiological data reporting an absence of comorbidity between ALS and epilepsy (Tartaglia et al., 2007), although case reports of co-occurrence in C9orf72 repeat expansion carriers exist (Capasso et al., 2016; Janssen et al., 2016; van den Ameele et al., 2018). Here, C9orf72 is linked to amyotrophic lateral sclerosis.