Vader [46] reported risk factors for post-discharge readmission or death in patients treated for acute heart failure, including male sex, non-use of angiotensin-converting enzyme inhibitors (ACEI) or angiotensin receptor blockers (ARB), lower baseline sodium, non-white race, lower systolic blood pressure at discharge or day 7, increased length of stay, and depression. The gene discussed is ACE; the disease is depressive symptom measurement.