Notably, the expression of the MIZ1 target genes Cdkn1a, Cdkn2a, and Cdkn2b, known to be repressed by MYC–MIZ1 complexes in cancer cells (Walz et al., 2014), were also similar between the LZ of MycVD and MycWT (Fig. S2 B). This evidence concerns the gene CDKN2A and cancer.