The result of OS analysis demonstrated that 7 DEG including C1R (HR = 1.900, P = 2.1E-05, Figure 5A), C1S (HR = 2.100, P = 1.5E-06, Figure 5B), IGLL5 (HR = 1.500, P = 0.016, Figure 5H), MMP7 (HR = 1.400, P = 0.031, Figure 5L), SERPINF1 (HR = 1.500, P = 0.006, Figure 5N), SLC38A5 (HR = 2.100, P = 1.5E-06, Figure 5O), and TGFBI (HR = 1.600, P = 0.002, Figure 5P) were associated with OS of patients with ccRCC. Here, SERPINF1 is linked to nonpapillary renal cell carcinoma.