INS and type 2 diabetes mellitus: A randomized controlled trial (RCT) of telemedicine with lifestyle adjustment and titration of metformin plus other oral hypoglycemics or insulin in a Danish type 2 diabetes population demonstrated a 14.6% drop in HbA1c (−15 mmol) with telemedicine and 10.6% (−10 mmol) reduction in their control group [34].