Genetic deletion of Yme1l in adult cardiomyocytes was shown to induce mitochondrial fragmentation (due to OMA1 cleaving L‐OPA1 to S‐OPA1), but did not affect mitochondrial respiration, and resulted in dilated cardiomyopathy at 20 weeks.56 This evidence concerns the gene OPA1 and dilated cardiomyopathy.