PPARG and Granuloma: We previously reported that instillation of MWCNT with or without ESAT-6 induced pulmonary granuloma formation in both wild-type C57Bl/6 and PPARγ KO mice 60 days later (19;20), though granuloma scores associated with MWCNT+ESAT-6 instillation were significantly (p≤0.05) greater in PPARγ KO mice (5.5 ± 0.2; n=6) than in wild-type (3.5 ± 0.62; n=6).