While the majority of selected molecules originated from activated myeloid cells in RA-ST (12 were within the top 100 of RA-ST transcripts coding secreted proteins in Fig. 6), we also included molecules that reflect activation of synovial fibroblasts (MMP3), endothelial cells (sSELE, sVCAM1), platelets (sSELP), activation of Th1- and Th17-cells (TNF, IFN, MIF), as well as early-differentiation of macrophages (SPP1). This evidence concerns the gene MIF and rheumatoid arthritis.