As cetuximab has been reported to have some immune influence in CRC patients by increasing the number of CD3+ T, CD8+ T and natural killer (NK) cells and reducing T-regulatory cells [20], we mapped 145 genes of interest to 1040 immune genes, and 10 immune genes were filtered out for subsequent studies about their association with treatment efficacy or drug resistance. Here, CD8A is linked to colorectal carcinoma.