NPPB and type 2 diabetes mellitus: However, after adjustment for age, and sex, only NT-proBNP (HR: 1.002, 95% CI 1.000–1.005, p = 0.02) and the glomerular filtration rate ≤ 80 ml/min (HR: 3.23, 95% CI 1.34–7.24, p = 0.047) were independent risk factors for patients with T2DM (Table 5).