Reduction in serum triacylglycerol level by 1–9% and serum uric acid level by 0.3–0.9 mg/dL, and increase in serum HDL-cholesterol by 6–9% by treatment with SGLT2 inhibitors have also been reported in patients with T2DM [13]. The gene discussed is SLC5A2; the disease is type 2 diabetes mellitus.