Importantly, among the LEF/TCF genes, our meta-analysis also corroborates a switch from relatively higher TCF7L2 (Figure 1D) and TCF7L1 (Figure 1C) expression in normal control to relatively higher TCF7 (Figure 1A) and LEF1 (Figure 1B) expression in tumor tissue. Here, TCF7L1 is linked to neoplasm.