ACE2 and COVID-19: COVID-19 could also induce new onset diabetes, by augmenting insulin resistance and/or by a direct action [155] on the islets of Langerhans; supporting this view, previous studies have shown that ACE2 can be a therapeutic target to ameliorate microcirculation in the islets [156], and ACE2 is known to be expressed by pancreatic beta cells [157,158,159,160,161,162].