ACE2 and COVID-19: Nevertheless, ACE2 is also expressed by endothelial cells [7,8], and other major clinical events usually observed in COVID-19 patients (e.g., high blood pressure [9,10,11,12,13], thrombosis [14,15,16] kidney disease [17,18], pulmonary embolism [19,20], cerebrovascular and neurologic disorders [21,22]) indicate that the virus is targeting the endothelium [23], one of the largest organs in the human body [24,25,26].