KRAS and lung carcinoma: Glycolytic gene expression, glucose uptake, and lactate secretion are increased in homozygote KRASG12D/G12D mutated lung cancer cells relative to KRASG12D/WT heterozygous (Kerr et al., 2016); therefore, the difference in glycolytic activity between classical (pancreatic) and squamous PDCLs may be a consequence of difference in KRAS copy number.