Vileigas Vileigas DF DF Deus Deus AF AF Silva Silva DCT DCT Tomasi Tomasi LC LC Campos Campos DHS DHS Adorni Adorni CS CS et al et al Saturated high-fat diet-induced obesity increases adenylate cyclase of myocardial b-adrenergic system and does not compromise cardiac function Saturated high-fat diet-induced obesity increases adenylate cyclase of myocardial b-adrenergic system and does not compromise cardiac function Physiol Rep Physiol Rep 2016 2016 4 4 17 17 e12914 e12914 27582064 27582064. The gene discussed is ADCY1; the disease is obesity due to melanocortin 4 receptor deficiency.