To that end, we performed this study to evaluate the changes in CD8+, CD4+, and FOXP3+ TILs in each compartment after PST, and investigated the association between TIL subset infiltration and survival in patients with breast cancer who were treated with anthracycline- or anthracycline plus taxane-based PST using pre- and post-PST specimens. This evidence concerns the gene FOXP3 and breast cancer.