By analyzing the correlations between high or low expression of both CAV1 and ATG4 in the cancer (S1 Table) or stroma cells(S2 Table) and the clinicopathologic features of EOC patients, we additionally found that high expression of both CAV1 and ATG4C protein in the stroma was significantly related to the histologic subtypes of EOC patients (P = 0.001). This evidence concerns the gene CAV1 and cancer.