Regression of the primary tumour was classified according to Becker as TRG1a (complete regression) in 17 cases (3.5%), TRG1b (<10% residual tumour) in 85 cases (18%), TRG2 (10–50% residual tumour) in 121 cases (25%) and TRG3 (>50% residual tumour) in 257 cases (53%) (see supplementary material, Table S1). Here, SAMM50 is linked to neoplasm.