SAMM50 and neoplasm: Tumour regression grade of the primary tumour also demonstrated a highly significant association with prognosis: TRG1 differed from TRG2 (p < 0.001; TRG1a versus TRG1b; p = 0.2) and TRG2 from TRG3 (p = 0.003), which showed even higher significant values in survival analysis compared to the original study with shorter follow‐up [21] (overall p < 0.001; HR = 1.757; 95% CI 1.514–2.041; see supplementary material, Figure S1).