Similar changes in phosphorylated PDH were measured in murine ovarian cancer Trp53−/−, Brca1−/−, myc, and Akt cells and in double Trp53/Tsc2‐deleted MEFs as compared to Trp53−/−, myc, and Akt cells and Trp53‐deleted MEFs (Fig EV2C and D). This evidence concerns the gene TSC2 and ovarian carcinoma.