The CD8+TIL density in the tumor area was significantly higher in the adenocarcinomas, and the Foxp3+TIL density in the stromal area was significantly higher in the squamous cell carcinomas, (CD8+TIL density in the tumor: P = .0018; Foxp3+TIL density in the stroma: P < .0001). This evidence concerns the gene FOXP3 and squamous cell carcinoma.