SIX1 and acute myeloid leukemia: Besides, a previous report indicated that the SIX1 can be transcriptional regulated by a transducer of WNT/β-catenin signaling, TCF7L2 in acute myelocytic leukemia (Zhang et al. 2019), and WNT/β-catenin signaling promotes skeletal muscle development by increasing SIX1 levels (Petropoulos, Skerjanc 2002).