TNFRSF11B mRNA expression in GC tissues was significantly higher than that in tissues from corresponding surgical margins (Fig. 1F, P<0.001).KM survival curve analysis showed that the 5-year OS rate of patients with high TNFRSF11B mRNA expression was lower than that of patients with low TNFRSF11B mRNA expression among the 160 patients (Fig.1G, P=0.0025). This evidence concerns the gene TNFRSF11B and gastric cancer.