Among these genes, KIAA1429, HNRNPC, YTHDC2, METTL3, WTAP, YTHDC1, and FTO were down expressed in lung adenocarcinoma, RBM15, ZC3H13, YTHDF1, YTHDF2, and ALKBH5 were up expressed (Figure 1A-B). The gene discussed is YTHDF1; the disease is lung adenocarcinoma.