CD8A and viral infectious disease: Lastly, CCR5 is a major chemoattracting receptor in CD8+ T cells that involves in various pathogenic conditions, including viral infections.24 The antiviral drugs, such as Selzentry (maraviroc) and Leronlimab (PRO 140), have been successfully used for treatment of AIDS.25 It is therefore of great interest to study whether these drugs can block cardiac infiltration of CD8+ T cells thereby reduce hypertensive cardiac injury of COVID-19 patients.