FLCN and polycystic kidney disease: Lastly, in ID29.1, a 66-year-old male with positive family history, ESRD at age 56, and bilateral polycystic kidneys, ES yielded a previously reported heterozygous FLCN missense variant (c.1523A>G, p.Lys508Arg)16 compatible with BHDS (Table 1, Fig. 4).