KMT2A and leukemia: To determine whether this observation applied to leukemia cells bearing different MLL-fusion partners, we analyzed MLL-fusion protein (MLL-N and fusion partner C-terminus if applicable) and H3K79me2 chromatin immunoprecipitation followed by deep sequencing (ChIP-seq) datasets from THP-130 and ML-231 cell lines (with MLL-AF9 and MLL-AF6 respectively), as well as from the MV4;1130, RS4;1132, and SEM33 cell lines which bear an MLL-AF4 fusion.