Results showed that HLA-A*11:01 (28.7% and 25.2%), HLA-B*40:01 (21.3% and 18.8%) and HLA-C*07:02 (33.3% and 19.4%) (Table 2) were the most major HLA class I genotypes for both AD patients and general population. The gene discussed is HLA-B; the disease is Alzheimer disease.