For that purpose, we used two models deriving from the human pancreatic cancer cell line T3M-4, control Sc cells expressing high levels of Galectin-3 and a representative mutant clone (Sh1 called Sh cells thereafter) where Galectin-3 expression was stably knocked-down by shRNA (Fig. S1). This evidence concerns the gene LGALS3 and pancreatic neoplasm.