In the PTSD group, CRP levels were significantly negatively associated with composite prefrontal-limbic [11C]PBR28 VT (Fig. 3a: β = −0.92, p = 0.029), and significantly positively associated with greater PTSD symptom severity measured as a normalized total CAPS score (Fig. 3b: R2 = 0.21, p = 0.037), confirming previous observations of an association between elevated CRP and PTSD symptomatology7,8. The gene discussed is CRP; the disease is post-traumatic stress disorder.