BCR and chronic myelogenous leukemia, BCR-ABL1 positive: In order to demonstrate the relevance of the CML, its receptor of AGE (RAGE) was immunohistochemically stained on the sequential frozen sections with the antibody against RAGE (rabbit polyclonal, ab3611, Abcam, UK, 1:500 dilution), and with the anti-CML antibody, using the BOND RX automated immunostainer as above.