In univariate logistic regression analyses, factors associated with the occurrence of cardiovascular disease events were an overexpression of HER-2 (HR 2.6 [1.21–5.56] p < 0.011) as well as UICC-stage III tumors or more (HR 5.47 [2.78–10.76] p < 0.001). This evidence concerns the gene ERBB2 and cardiovascular disorder.