After IL-17 inhibitor treatment, the most frequent adverse events reported were treatment-emergent adverse events (57.2%, 660/1153 vs. placebo 51.4%, 297/578) (RR = 1.11, 95% CI 1.01 to 1.22, p = 0.03) (Fig. 3a) and non-severe infections (27.4%, 211/770 vs. placebo 15.0%, 58/384) (RR = 1.82, 95% CI 1.40 to 2.37, p < 0.001) (Fig. 3d). The gene discussed is IL17A; the disease is infection.