This comparison revealed that anti-VEGF treatment starting at day 4 post-tumor implantation affects tumor viscoelasticity as tumors in untreated animals were significantly softer and had lower values of the phase angle Y. Lower phase angle indicates that the tumor behaves more like an elastic material, compared to tumors in animals treated with B20 anti-VEGF-antibody (p = 0.02 for |G∗| and p = 0.0071 for Y; Table 1; Fig. 2d, f and Fig. 4a). Here, VEGFA is linked to neoplasm.