However, when RT was delivered to sc tumor together with administration of anti-CD73 mAb or isotype control, the growth of sc tumor was significantly delayed in mice treated with anti-CD73 mAb (p < 0.05, at day 18 and later) and tumor volume at day 28 was reduced to about 50% (Fig. 3a, b). The gene discussed is NT5E; the disease is neoplasm.