As AXL receptor signaling participates in the downmodulation of interferon-related host immune responses to promote viral infection, inhibiting AXL function might be a new therapeutic avenue toward reducing the transmission of some of the most troublesome emerging enveloped viruses, including dengue, West Nile, Ebola, lentivirus, and most recently, Zika [99,100]. This evidence concerns the gene AXL and dengue disease.