Low risk of malignancy- negative association of TATI expression was positively correlated based on tumour stage (p = 0.048) and poor differentiation (p = 0.013). Significant differences were observed between TATI-positive and negative specimens in PFS and OS (Log-rank test, p = 0.003, 0.003). In a group of patients with BC undergoing RC TATI expression was independent protective factor. Moreover, TATI expression could enhance prognostic value of p53. Here, TP53 is linked to neoplasm.