Low risk of malignancy- negative association of TATI expression was positively correlated based on tumour stage (p = 0.048) and poor differentiation (p = 0.013). Significant differences were observed between TATI-positive and negative specimens in PFS and OS (Log-rank test, p = 0.003, 0.003). In a group of patients with BC undergoing RC TATI expression was independent protective factor. Moreover, TATI expression could enhance prognostic value of p53. This evidence concerns the gene TP53 and breast cancer.