CFTR and cystic fibrosis: Currently, researchers are working on different approaches, some of them aimed to handle the basic molecular defect in CF, by restoring proper function to the CFTR protein or correcting its production process so that a normal protein can be build up [50,51,52,53,54], others directed to controlling the clinical manifestations of the diseases, including inflammation, infection and mucociliary clearance, mostly for patients with irreversible lung damage [55,56,57,58,59].